Assess students' ability to conceptually design and critically evaluate a CRISPR-based gene drive program to suppress an invasive Aedes mosquito population, focusing on high-level principles of molecular confinement (mechanisms to limit or reverse spread), ecological risk assessment and mitigation, population and ecosystem modeling (assumptions and uncertainty), research-proposal components (hypotheses, objectives, ethical/regulatory considerations, stakeholder engagement, monitoring and adaptive management), and a non-actionable experimental validation plan describing study design rationale, outcome metrics, and decision points. Responses must remain at a conceptual, policy and design level; do not require procedural laboratory steps or operational protocols.