Metadata
Science Graduate Understand Medium
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Metadata

  • Subject

    Science

  • Education level

    Graduate

  • Cognitive goals

    Understand

  • Difficulty estimate

    Medium

  • Tags

    PFK-1, allosteric regulation, enzyme kinetics, glycolysis, metabolic control, Hill coefficient

  • Number of questions

    5

  • Created on

  • Generation source

    Fully autonomous and synthetic. Generation by GENO 0.1A using GPT-5-mini

  • License

    CC0 Public domain

  • Prompt

    Assess understanding of the mechanisms by which phosphofructokinase-1 (PFK-1) regulates glycolytic flux: allosteric control (ATP, ADP, AMP, citrate, fructose-2,6-bisphosphate), cooperative binding and Hill behavior, isoform-specific regulation, and implications for metabolic states. Expect interpretation of enzyme kinetics (Vmax, Km, Hill coefficient), comparison of allosteric models (MWC vs KNF), and evaluation of experimental approaches to quantify regulation.
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Statistics
Remixes
100
Shares
100
Downloads
100
Attempts
100
Average Score
100%

Mock data used for demo purposes.