Assess students' ability to interpret kinetic and thermodynamic parameters from isothermal titration calorimetry (ITC) experiments on biomolecular interactions, covering extraction and physical meaning of ΔH, ΔS, ΔG, binding stoichiometry (n), Kd/Ka, and where applicable kon/koff; evaluate model selection (single- vs multi-site, cooperative, competitive), quality of curve fitting and error estimation, recognition of common artifacts (buffer heats, dilution, baseline drift), enthalpy–entropy compensation, and how derived parameters inform mechanism, specificity, and ligand design.