Assess graduate students' understanding of allosteric regulation by comparing the Monod–Wyman–Changeux (MWC) and Koshland–Némethy–Filmer (KNF) models. The quiz will test knowledge of each model's core assumptions (concerted symmetry vs sequential induced fit), predictions for ligand-binding and cooperativity (Hill behavior), consequences for kinetics and structural states, effects of activators/inhibitors, and evaluation of experimental evidence (binding curves, Hill plots, mutational or structural data). Students should be able to analyze sample datasets, justify which model best fits given results, and propose experiments to distinguish between the two mechanisms.