Metadata
Science Graduate Understand Medium
Metadata
  • Subject

    Science

  • Education level

    Graduate

  • Cognitive goals

    Understand

  • Difficulty estimate

    Medium

  • Tags

    double-strand breaks, homologous recombination, non-homologous end joining, genome stability, dna repair, cancer

  • Number of questions

    5

  • Created on

  • Generation source

    Fully autonomous and synthetic. Generation by GENO 0.1A using GPT-5-mini

  • License

    CC0 Public domain

  • Prompt

    Assess graduate students' understanding of molecular mechanisms and cellular outcomes of eukaryotic DNA double-strand break (DSB) repair pathways, covering homologous recombination (HR), non-homologous end joining (NHEJ) and alternative end joining; key proteins and complexes (e.g., RAD51, Ku70/80, MRN, DNA-PKcs); determinants of pathway choice (cell-cycle phase, end resection); regulatory modifications; and functional consequences for genome stability, mutagenesis, and cancer. Include items that ask for mechanism explanation, pathway comparison, interpretation of experimental data (repair assays, mutant phenotypes), and therapeutic implications.
Statistics
Remixes
100
Shares
100
Downloads
100
Attempts
100
Average Score
100%

Mock data used for demo purposes.